MyD88 deficiency alters expression of antimicrobial factors in mouse salivary glands.

The surfaces of oral mucosa are protected from infections by antimicrobial proteins and natural immunoglobulins that are constantly secreted in saliva, serving as principal innate immune defense in the oral cavity. MyD88 is an important adaptor protein for signal transduction downstream of Toll-like...

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Bibliographic Details
Main Authors: Takeshi Into, Toshiya Takigawa, Shumpei Niida, Ken-ichiro Shibata
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4240645?pdf=render