Chemopreventive, apoptotic, antiangiogenic efficacy of Hesperidin via mitigation of epigenetic alterations of global DNA methylation and targeting microRNA in a rat model of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) accounting about 75% of hepatic neoplasia, making it the most common kind of liver cancer worldwide. So, this study was planned to evaluate the beneficial chemopreventive efficacy of hesperidin (Hes) in experimental model of Diethyl nitrosamine (DEN) / Carbon tetrachl...

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Bibliographic Details
Main Authors: A'laa E. Al-semelawy, Samy A. Hussein, Hussein A. Ali, Yakout A. EL-Senosi, Afaf D. Abdel Magid, Shawky A. Mostafa
Format: Article
Language:English
Published: Assiut University 2024-04-01
Series:Journal of Advanced Veterinary Research
Subjects:
Online Access:https://advetresearch.com/index.php/AVR/article/view/1826