A Robust Nanoparticle Platform for RNA Interference in Macrophages to Suppress Tumor Cell Migration

Macrophages are one of the most abundant immune cells in the solid tumor and their increased density is associated with the specific pathological features of cancers, including invasiveness, metastasis, immunosuppression, neovascularization, and poor response to therapy. Therefore, reprogramming mac...

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Bibliographic Details
Main Authors: Shi Liang, Junmeng Zheng, Wei Wu, Quan Li, Phei Er Saw, Jianing Chen, Xiaoding Xu, Herui Yao, Yandan Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01465/full