Development of expression systems for the production of recombinant human Fas ligand extracellular domain derivatives using <em>Pichia pastoris</em> and preparation of the conjugates by site-specific chemical modifications: A review

Development of expression systems for the production of recombinant human Fas ligand extracellular domain derivatives using <em>Pichia pastoris</em> and preparation of the conjugates by site-specific chemical modifications: A review

Human Fas ligand extracellular domain (hFasLECD) is a biomedically important glycoprotein with three potential N-linked carbohydrate-chain attachment sites. hFasLECD can induce an apoptotic cell-death in many malignant cells. Hence, the creation of novel molecular tools exhibiting useful biological...

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Bibliographic Details
Main Author: Michiro Muraki
Format: Article
Language:English
Published: AIMS Press 2018-01-01
Series:AIMS Bioengineering
Subjects:
human Fas ligand
extracellular domain
heterologous expression system
<em>Pichia pastoris</em>
site-specific chemical modification
conjugation
iEDDA reaction
medical applications
Online Access:http://www.aimspress.com/Bioengineering/article/1803/fulltext.html

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http://www.aimspress.com/Bioengineering/article/1803/fulltext.html

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