T cell repertoire profiling in allografts and native tissues in recipients with COVID–19 after solid organ transplantation: Insight into T cell–mediated allograft protection from viral infection

T cell repertoire profiling in allografts and native tissues in recipients with COVID–19 after solid organ transplantation: Insight into T cell–mediated allograft protection from viral infection

IntroductionThe effects of the SARS-CoV-2 virus on the body, and why the effects are more severe in certain patients, remain incompletely understood. One population of special interest is transplant recipients because of their immunosuppressed state. Understanding the pathophysiology of graft dysfun...

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Bibliographic Details
Main Authors: Jianing Fu, Dylan Rust, Zhou Fang, Wenyu Jiao, Stephen Lagana, Ibrahim Batal, Bryan Chen, Sarah Merl, Rebecca Jones, Megan Sykes, Joshua Weiner
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
COVID–19
T cell repertoire analysis
transplant recipients
immunosuppressed
viral response
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1056703/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1056703/full

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