HLA-A confers an HLA-DRB1 independent influence on the risk of multiple sclerosis.

HLA-A confers an HLA-DRB1 independent influence on the risk of multiple sclerosis.

A recent high-density linkage screen confirmed that the HLA complex contains the strongest genetic factor for the risk of multiple sclerosis (MS). In parallel, a linkage disequilibrium analysis using 650 single nucleotide polymorphisms (SNP) markers of the HLA complex mapped the entire genetic effec...

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Bibliographic Details
Main Authors: Boel Brynedal, Kristina Duvefelt, Gudrun Jonasdottir, Izaura M Roos, Eva Akesson, Juni Palmgren, Jan Hillert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-07-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0000664

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https://doi.org/10.1371/journal.pone.0000664

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