KIR gene content imputation from single-nucleotide polymorphisms in the Finnish population
The killer cell immunoglobulin-like receptor (KIR) gene cluster on chromosome 19 encodes cell surface glycoproteins that bind class I human leukocyte antigen (HLA) molecules as well as some other ligands. Through regulation of natural killer (NK) cell activity KIRs participate in tumour surveillance...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2022-01-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/12692.pdf |