KIR gene content imputation from single-nucleotide polymorphisms in the Finnish population

The killer cell immunoglobulin-like receptor (KIR) gene cluster on chromosome 19 encodes cell surface glycoproteins that bind class I human leukocyte antigen (HLA) molecules as well as some other ligands. Through regulation of natural killer (NK) cell activity KIRs participate in tumour surveillance...

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Bibliographic Details
Main Authors: Jarmo Ritari, Kati Hyvärinen, Jukka Partanen, Satu Koskela
Format: Article
Language:English
Published: PeerJ Inc. 2022-01-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/12692.pdf