Phorbol ester promotes histone H3-Ser10 phosphorylation at the LDL receptor promoter in a protein kinase C-dependent manner

Histone modification is emerging as a major regulatory mechanism for modulating gene expression by altering the accessibility of transcription factors to DNA. This study unravels the relationship between histone H3 modifications and LDL receptor induction, focusing also on routes by which phosphoryl...

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Bibliographic Details
Main Authors: Wei Huang, Vachaspati Mishra, Sanjay Batra, Ishan Dillon, Kamal D. Mehta
Format: Article
Language:English
Published: Elsevier 2004-08-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520313146