KIF5A and KLC1 expression in Alzheimer’s disease: relationship and genetic influences [version 2; peer review: 2 approved, 1 approved with reservations]

Background: Early disturbances in axonal transport, before the onset of gross neuropathology, occur in a spectrum of neurodegenerative diseases including Alzheimer’s disease. Kinesin superfamily motor proteins (KIFs) are responsible for anterograde protein transport within the axon of various cellul...

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Bibliographic Details
Main Authors: Seth Love, Neil Scolding, Alastair Wilkins, Scott Miners, Kelly Hares
Format: Article
Language:English
Published: F1000 Research Ltd 2019-06-01
Series:AMRC Open Research
Subjects:
Online Access:https://healthopenresearch.org/articles/1-1/v2