Interaction between IGF-IR and ER induced by E2 and IGF-I.

Interaction between IGF-IR and ER induced by E2 and IGF-I.

Estrogen receptor (ER) is a nuclear receptor and the insulin-like growth factor-I (IGF-I) receptor (IGF-IR) is a transmembrane tyrosine kinase receptor. Estrogen and IGF-I are known to have synergistic effects on the growth of breast cancer cells. Recently, non-nuclear effects of ER have been under...

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Bibliographic Details
Main Authors: Zhenghong Yu, Weimin Gao, Enze Jiang, Fang Lu, Luo Zhang, Zhaorong Shi, Xinxing Wang, Longbang Chen, Tangfeng Lv
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3660452?pdf=render

Internet

http://europepmc.org/articles/PMC3660452?pdf=render

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