A synergistic therapy against influenza virus A/H1N1/PR8 by a HA1 specific neutralizing single-domain VL and an RNA hydrolyzing scFv

A synergistic therapy against influenza virus A/H1N1/PR8 by a HA1 specific neutralizing single-domain VL and an RNA hydrolyzing scFv

The emergence of anti-influenza drug-resistant strains poses a challenge for influenza therapy due to mutations in the virus’s surface protein. Recently, there has been increasing interest in combination therapy consisting of two or more drugs as a potential alternative approach, aiming to enhance t...

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Bibliographic Details
Main Authors: Phuong Thi Hoang, Quynh Xuan Thi Luong, Ramadhani Qurrota Ayun, Yongjun Lee, Kwang-Ji Oh, Taehyun Kim, Taek-Kyun Lee, Sukchan Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Microbiology
Subjects:
bio-panning
synergistic effect
influenza virus
3D8 scFv
neutralizing antibodies
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1355599/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2024.1355599/full

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