The Proteolytic Regulation of Virus Cell Entry by Furin and Other Proprotein Convertases

A wide variety of viruses exploit furin and other proprotein convertases (PCs) of the constitutive protein secretion pathway in order to regulate their cell entry mechanism and infectivity. Surface proteins of enveloped, as well as non-enveloped, viruses become processed by these proteases intracell...

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Bibliographic Details
Main Author: Gonzalo Izaguirre
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/11/9/837