Strategies To Assess Hypoxic/HIF-1-Active Cancer Cells for the Development of Innovative Radiation Therapy

Local tumor recurrence and distant tumor metastasis frequently occur after radiation therapy and result in the death of cancer patients. These problems are caused, at least in part, by a tumor-specific oxygen-poor microenvironment, hypoxia. Oxygen-deprivation is known to inhibit the chemical ionizat...

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Bibliographic Details
Main Authors: Masahiro Hiraoka, Hiroshi Harada, Yuxi Zhu, Lihua Zeng, Chan Joo Yeom
Format: Article
Language:English
Published: MDPI AG 2011-09-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/3/3/3610/