<named-content content-type="genus-species">Aspergillus fumigatus</named-content> G-Protein Coupled Receptors GprM and GprJ Are Important for the Regulation of the Cell Wall Integrity Pathway, Secondary Metabolite Production, and Virulence

<named-content content-type="genus-species">Aspergillus fumigatus</named-content> G-Protein Coupled Receptors GprM and GprJ Are Important for the Regulation of the Cell Wall Integrity Pathway, Secondary Metabolite Production, and Virulence

ABSTRACT G-protein coupled receptors (GPCRs) are extracellular signaling receptors that sense environmental cues. Fungi sense their environment primarily through GPCR-mediated signaling pathways, which, in turn, regulate fungal development, metabolism, virulence, and mycotoxin biosynthesis. Aspergil...

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Bibliographic Details
Main Authors: Aílton Pereira da Costa Filho, Guilherme Thomaz Pereira Brancini, Patrícia Alves de Castro, Clara Valero, Jaire Alves Ferreira Filho, Lilian Pereira Silva, Marina Campos Rocha, Iran Malavazi, João Guilherme de Moraes Pontes, Taícia Fill, Roberto Nascimento Silva, Fausto Almeida, Jacob L. Steenwyk, Antonis Rokas, Thaila F. dos Reis, Laure N. A. Ries, Gustavo H. Goldman
Format: Article
Language:English
Published: American Society for Microbiology 2020-10-01
Series:mBio
Subjects:
Aspergillus fumigatus
G-protein coupled receptor
cell wall
secondary metabolites
virulence
Online Access:https://journals.asm.org/doi/10.1128/mBio.02458-20

Internet

https://journals.asm.org/doi/10.1128/mBio.02458-20

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