Artemisinin DNA Base Interaction Studies in Presence of Fe(II): LC/TOF MS Separation of Reaction Products

Artemisinin (ART) is a sesquiterpene lactone and a popular malaria drug with potential anticancer properties. In this work, LC/TOF/MS, was used to investigate the reaction of ART with DNA bases. ART-deoxyadenosine and ART-deoxycytidine interactions, were studied in the presence of iron II ions. ART-...

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Bibliographic Details
Main Authors: Kogila Oke, Amos Mugweru
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Separations
Subjects:
Online Access:https://www.mdpi.com/2297-8739/8/9/161