Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity.

Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity.

SARS-CoV-2 is the novel coronavirus that is the causative agent of COVID-19, a sometimes-lethal respiratory infection responsible for a world-wide pandemic. The envelope (E) protein, one of four structural proteins encoded in the viral genome, is a 75-residue integral membrane protein whose transmem...

Полное описание

Библиографические подробности
Главные авторы: Sang Ho Park, Haley Siddiqi, Daniela V Castro, Anna A De Angelis, Aaron L Oom, Charlotte A Stoneham, Mary K Lewinski, Alex E Clark, Ben A Croker, Aaron F Carlin, John Guatelli, Stanley J Opella
Формат: Статья
Язык:English
Опубликовано: Public Library of Science (PLoS) 2021-05-01
Серии:PLoS Pathogens
Online-ссылка:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009519&type=printable

Internet

https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009519&type=printable

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