Impact of Cabozantinib Exposure on Proteinuria and Muscle Toxicity in Patients with Unresectable Hepatocellular Carcinoma

Impact of Cabozantinib Exposure on Proteinuria and Muscle Toxicity in Patients with Unresectable Hepatocellular Carcinoma

This prospective study investigated the impact of cabozantinib exposure on proteinuria and muscle toxicity, in a cohort of 14 Japanese patients with unresectable hepatocellular carcinoma (uHCC). We measured the trough concentration of cabozantinib (C<sub>trough</sub>) weekly for 6 weeks...

Full description

Bibliographic Details
Main Authors: Hironao Okubo, Hitoshi Ando, Yusuke Takasaki, Eisuke Nakadera, Yuka Fukuo, Shuichiro Shiina, Kenichi Ikejima
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pharmaceuticals
Subjects:
cabozantinib
pharmacokinetic analysis
muscle enzyme
hepatocellular carcinoma
Online Access:https://www.mdpi.com/1424-8247/15/12/1460

Internet

https://www.mdpi.com/1424-8247/15/12/1460

Similar Items