The conserved AAA ATPase PCH-2 distributes its regulation of meiotic prophase events through multiple meiotic HORMADs in C. elegans.

The conserved AAA ATPase PCH-2 distributes its regulation of meiotic prophase events through multiple meiotic HORMADs in C. elegans.

During meiotic prophase, the essential events of homolog pairing, synapsis, and recombination are coordinated with meiotic progression to promote fidelity and prevent aneuploidy. The conserved AAA+ ATPase PCH-2 coordinates these events to guarantee crossover assurance and accurate chromosome segrega...

Full description

Bibliographic Details
Main Authors: Anna E Russo, Stefani Giacopazzi, Alison Deshong, Malaika Menon, Valery Ortiz, Kaori M Ego, Kevin D Corbett, Needhi Bhalla
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-04-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010708

Internet

https://doi.org/10.1371/journal.pgen.1010708

Similar Items