3579 The role of CypD/mPTP during osteogenic differentiation - a potential target to prevent bone loss

OBJECTIVES/SPECIFIC AIMS: The study aims to further investigate how cyclophilin D (CypD), the key mPTP opening regulator, affects BMSCs fate and to determine potential regulatory mechanisms involved in CypD regulation during osteogenesis. METHODS/STUDY POPULATION: We evaluated CypD mRNA expression i...

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Bibliographic Details
Main Authors: Rubens Sautchuk, Brianna H. Shares, Roman A. Eliseev
Format: Article
Language:English
Published: Cambridge University Press 2019-03-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S205986611900058X/type/journal_article