Transplantation of insulin-producing cells derived from human mesenchymal stromal/stem cells into diabetic humanized mice

Transplantation of insulin-producing cells derived from human mesenchymal stromal/stem cells into diabetic humanized mice

Abstract Background The purpose of this study was to investigate allogenic immune responses following the transplantation of insulin-producing cells (IPCs) differentiated from human adipose tissue-derived stem cells (hAT-MSCs) into humanized mice. Methods hAT-MSCs were isolated from liposuction aspi...

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Main Authors: Mohamed A. Ghoneim, Mahmoud M. Gabr, Ayman F. Refaie, Sawsan M. El-Halawani, Mohga M. Al-issawi, Batoul L. Elbassiouny, Mai A. Abd El Kader, Amani M. Ismail, Mona F. Zidan, Mary S. Karras, Raghda W. Magar, Sherry M. Khater, Sylvia A. Ashamallah, Mahmoud M. Zakaria, Malgorzata Kloc
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stromal cells
Differentiation
Transplantation
Humanized mice
Insulin producing cells
Diabetes
Online Access:https://doi.org/10.1186/s13287-022-03048-y

Internet

https://doi.org/10.1186/s13287-022-03048-y

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