mTOR Inhibitor Use Is Associated With a Favorable Outcome of COVID-19 in Patients of Kidney Transplant: Results of a Retrospective Study

mTOR Inhibitor Use Is Associated With a Favorable Outcome of COVID-19 in Patients of Kidney Transplant: Results of a Retrospective Study

IntroductionIn solid organ transplant recipients, COVID-19 is associated with a poor prognosis because of immunosuppression. Some studies suggest a potential therapeutic role of mammalian Target of Rapamycin (mTOR) inhibitors in SARS-CoV-2 infection. This study aimed to assess the impact of mTOR emp...

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Bibliographic Details
Main Authors: Biagio Pinchera, Lorenzo Spirito, Antonio Riccardo Buonomo, Maria Foggia, Rosa Carrano, Fabrizio Salemi, Elisa Schettino, Fortuna Papa, Roberto La Rocca, Felice Crocetto, Luigi Napolitano, Riccardo Villari, Ivan Gentile
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Medicine
Subjects:
kidney transplant
SARS-CoV-2
COVID-19
mTOR inhibitors
immunosuppressive therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.852973/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.852973/full

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