Characterizing the Ablative Effects of Histotripsy for Osteosarcoma: In Vivo Study in Dogs

Osteosarcoma (OS) is a malignant bone tumor treated by limb amputation or limb salvage surgeries and chemotherapy. Histotripsy is a non-thermal, non-invasive focused ultrasound therapy using controlled acoustic cavitation to mechanically disintegrate tissue. Recent ex vivo and in vivo pilot studies...

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Bibliographic Details
Main Authors: Lauren N. Ruger, Alayna N. Hay, Elliana R. Vickers, Sheryl L. Coutermarsh-Ott, Jessica M. Gannon, Hannah S. Covell, Gregory B. Daniel, Paul F. Laeseke, Timothy J. Ziemlewicz, Katharine R. Kierski, Brittany J. Ciepluch, Eli Vlaisavljevich, Joanne L. Tuohy
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cancers
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Online Access:https://www.mdpi.com/2072-6694/15/3/741