Heat shock protein 90 inhibitor RGRN-305 potently attenuates skin inflammation

Heat shock protein 90 inhibitor RGRN-305 potently attenuates skin inflammation

IntroductionChronic inflammatory skin diseases may have a profound negative impact on the quality of life. Current treatment options may be inadequate, offering an unsatisfactory response or side effects. Therefore, ongoing efforts exist to identify novel effective and safe treatments. Heat shock pr...

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Bibliographic Details
Main Authors: Hakim Ben Abdallah, Sabine Seeler, Anne Bregnhøj, Gautam Ghatnekar, Lasse S. Kristensen, Lars Iversen, Claus Johansen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
HSP90 (heat shock protein 90)
novel therapeutic strategy
inflammation
small molecule
12-O-Tetradecanoylphorbol-13-acetate
keratinocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1128897/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1128897/full

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