Changes in Plasma Pyruvate and TCA Cycle Metabolites upon Increased Hepatic Fatty Acid Oxidation and Ketogenesis in Male Wistar Rats

Altered hepatic mitochondrial fatty acid β-oxidation and associated tricarboxylic acid (TCA) cycle activity contributes to lifestyle-related diseases, and circulating biomarkers reflecting these changes could have disease prognostic value. This study aimed to determine hepatic and systemic changes i...

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Bibliographic Details
Main Authors: Simon Nitter Dankel, Tine-Lise Kalleklev, Siri Lunde Tungland, Marit Hallvardsdotter Stafsnes, Per Bruheim, Thomas Aquinas Aloysius, Carine Lindquist, Jon Skorve, Ottar Kjell Nygård, Lise Madsen, Bodil Bjørndal, Magne Olav Sydnes, Rolf Kristian Berge
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/21/15536