Susceptibility of Multiple Primary Cancers in Patients With Head and Neck Cancer: Nature or Nurture?

Susceptibility of Multiple Primary Cancers in Patients With Head and Neck Cancer: Nature or Nurture?

Multiple primary cancers (MPCs) are major obstacles to long-term survival in head and neck cancer (HNSCC), however, the molecular mechanism underlying multiple carcinogenesis remains unclear. “Field cancerization” is a classical theory to elaborate the malignant progression of MPCs. Apart from envir...

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Bibliographic Details
Main Authors: Wei-long Zhang, Zhuo-li Zhu, Mei-chang Huang, Ya-Jie Tang, Ya-ling Tang, Xin-hua Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Oncology
Subjects:
head and neck cancer
multiple primary cancer
field cancerization
cancer-associated fibroblasts
genetic factor
biomarker
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01275/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.01275/full

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