A heparan-sulfate-bearing syndecan-1 glycoform is a distinct surface marker for intra-tumoral myeloid-derived suppressor cells

A heparan-sulfate-bearing syndecan-1 glycoform is a distinct surface marker for intra-tumoral myeloid-derived suppressor cells

Summary: Myeloid-derived suppressor cells (MDSCs) infiltrate cancer tissue, promote tumor growth, and are associated with resistance to cancer therapies. However, there is no practical approach available to distinguish MDSCs from mature counterparts inside tumors. Here, we show that a recently isola...

Full description

Bibliographic Details
Main Authors: Thomas Welte, Junhua Mai, Zhe Zhang, Shaohui Tian, Guodong Zhang, Yitian Xu, Licheng Zhang, Shu-shia Chen, Tian Wang, Haifa Shen
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:iScience
Subjects:
Molecular biology
Immunology
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221013183

Internet

http://www.sciencedirect.com/science/article/pii/S2589004221013183

Similar Items