Beyond rotamers: a generative, probabilistic model of side chains in proteins

<p>Abstract</p> <p>Background</p> <p>Accurately covering the conformational space of amino acid side chains is essential for important applications such as protein design, docking and high resolution structure prediction. Today, the most common way to capture this confo...

Full description

Bibliographic Details
Main Authors: Frellsen Jes, Paluszewski Martin, Boomsma Wouter, Harder Tim, Johansson Kristoffer E, Hamelryck Thomas
Format: Article
Language:English
Published: BMC 2010-06-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/306