Long term exposure of saxitoxin induced cognitive deficits and YAP1 cytoplasmic retention

Long term exposure of saxitoxin induced cognitive deficits and YAP1 cytoplasmic retention

While most studies assessed the acute toxicity of saxitoxin (STX), fewer studies focus on the long-term degenerative effects of STX on the central nervous system. We investigated the cognitive impairment and hippocampal damages of 6 months’ exposure of low-dose STX to C57BL/6NJ mice with behavioral...

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Bibliographic Details
Main Authors: Shenpan Li, Xiao Chen, Qian Sun, Xiaohu Ren, Jiacheng Zhong, Li Zhou, Hongyu Zhang, Guowei Li, Yungang Liu, Jianjun Liu, Haiyan Huang
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Saxitoxin
Cognitive deficits
YAP1
Hippo signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323001495

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http://www.sciencedirect.com/science/article/pii/S0147651323001495

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