Ascorbate mediates the non-enzymatic reduction of nitrite to nitric oxide

Nitric oxide (NO•) generated by nitric oxide synthases is involved in many physiological and pathophysiological processes. However, non-enzymatic formation of NO• also occurs in vivo. Here we investigated the production of NO• from nitrite, as facilitated by ascorbate, over the pH range of 2.4–7.4....

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Bibliographic Details
Main Authors: Juan Du, Milos R. Filipović, Brett A. Wagner, Garry R. Buettner
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Advances in Redox Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S266713792300019X