Dissecting the shared genetic landscape of anxiety, depression, and schizophrenia

Dissecting the shared genetic landscape of anxiety, depression, and schizophrenia

Abstract Background Numerous studies highlight the genetic underpinnings of mental disorders comorbidity, particularly in anxiety, depression, and schizophrenia. However, their shared genetic loci are not well understood. Our study employs Mendelian randomization (MR) and colocalization analyses, al...

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Bibliographic Details
Main Authors: Yiming Tao, Rui Zhao, Bin Yang, Jie Han, Yongsheng Li
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Journal of Translational Medicine
Subjects:
Anxiety
Depression
Schizophrenia
Shared genetic architecture
Drug targets
Online Access:https://doi.org/10.1186/s12967-024-05153-3

Internet

https://doi.org/10.1186/s12967-024-05153-3

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