In silico designing of multiepitope-based-peptide (MBP) vaccine against MAPK protein express for Alzheimer's disease in Zebrafish

In silico designing of multiepitope-based-peptide (MBP) vaccine against MAPK protein express for Alzheimer's disease in Zebrafish

Understanding the role of the mitogen-activated protein kinases (MAPKs) signalling pathway is essential in advancing treatments for neurodegenerative disorders like Alzheimer's. In this study, we investigate in-silico techniques involving computer-based methods to extract the MAPK1 sequence. Ou...

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Bibliographic Details
Main Authors: Yasir Arfat, Imran Zafar, Sheikh Arslan Sehgal, Mazhar Ayaz, Muhammad Sajid, Jamal Muhammad Khan, Muhammad Ahsan, Mohd Ashraf Rather, Azmat Ali Khan, Jamilah M. Alshehri, Shopnil Akash, Eugenie Nepovimova, Kamil Kuca, Rohit Sharma
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Heliyon
Subjects:
Pharmacophore
Virtual screening
Molecular docking
Multiepitope
Vaccine design
MAPK1
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023094124

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http://www.sciencedirect.com/science/article/pii/S2405844023094124

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