Vascular Endothelial Growth Factor Receptor, fms-Like Tyrosine Kinase-1 (Flt-1), as a Novel Binding Partner for SARS-CoV-2 Spike Receptor-Binding Domain

Vascular Endothelial Growth Factor Receptor, fms-Like Tyrosine Kinase-1 (Flt-1), as a Novel Binding Partner for SARS-CoV-2 Spike Receptor-Binding Domain

Angiotensin-converting enzyme 2 (ACE2) and neuropilin 1, a vascular endothelial growth factor (VEGF) receptor, were identified to bind to the SARS-CoV-2 spike receptor-binding domain (spike RBD). In silico analysis based on 3D structure, multiple sequence alignment, and molecular docking of second d...

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Bibliographic Details
Main Authors: Adel Zaid I. Mutahar, Manjunath Devaramani, Renu Dayal, Dinesh Kumar Saini, Paramahans V. Salimath, Bharathi P. Salimath
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
recombinant spike RBD
2-domain soluble Flt-1
binding partners
antibodies
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.906063/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.906063/full

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