Extracellular vesicles derived from human ES-MSCs protect retinal ganglion cells and preserve retinal function in a rodent model of optic nerve injury

Extracellular vesicles derived from human ES-MSCs protect retinal ganglion cells and preserve retinal function in a rodent model of optic nerve injury

Abstract Background Retinal and/or optic nerve injury is one of the leading causes of blindness due to retinal ganglion cell (RGC) degeneration. There have been extensive efforts to suppress this neurodegeneration. Various somatic tissue-derived mesenchymal stem cells (MSCs) demonstrated significant...

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Bibliographic Details
Main Authors: Seyedeh-Zahra Seyedrazizadeh, Sara Poosti, Abdoreza Nazari, Mehdi Alikhani, Faezeh Shekari, Farzad Pakdel, Koorosh Shahpasand, Leila Satarian, Hossein Baharvand
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Stem Cell Research & Therapy
Subjects:
Human embryonic stem cells
Mesenchymal stem cells
Optic nerve crush
Extracellular vesicle
Cis P- tau
Online Access:http://link.springer.com/article/10.1186/s13287-020-01702-x

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http://link.springer.com/article/10.1186/s13287-020-01702-x

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