Cellular Clearance and Biological Activity of Calciprotein Particles Depend on Their Maturation State and Crystallinity

Cellular Clearance and Biological Activity of Calciprotein Particles Depend on Their Maturation State and Crystallinity

Background: The liver-derived plasma protein fetuin-A is a systemic inhibitor of ectopic calcification. Fetuin-A stabilizes saturated mineral solutions by forming colloidal protein-mineral complexes called calciprotein particles (CPP). CPP are initially spherical, amorphous and soft, and are referre...

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Bibliographic Details
Main Authors: Sina Köppert, Andrea Büscher, Anne Babler, Ahmed Ghallab, Eva M. Buhl, Eicke Latz, Jan G. Hengstler, Edward R. Smith, Willi Jahnen-Dechent
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Immunology
Subjects:
calciprotein particle
calcification
inflammation
phosphate
fetuin-A
plasma protein
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01991/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01991/full

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