Neuroimmune Regulation in Sepsis-Associated Encephalopathy: The Interaction Between the Brain and Peripheral Immunity

Neuroimmune Regulation in Sepsis-Associated Encephalopathy: The Interaction Between the Brain and Peripheral Immunity

Sepsis-associated encephalopathy (SAE), the most popular cause of coma in the intensive care unit (ICU), is the diffuse cerebral damage caused by the septic challenge. SAE is closely related to high mortality and extended cognitive impairment in patients in septic shock. At present, many studies hav...

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Bibliographic Details
Main Authors: Yu-xiao Liu, Yang Yu, Jing-peng Liu, Wen-jia Liu, Yang Cao, Run-min Yan, Yong-ming Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Neurology
Subjects:
sepsis-associated encephalopathy
neuroendocrine–immune network
hypothalamic–pituitary–adrenal axis
cholinergic anti-inflammatory pathway
neuroinflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.892480/full

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https://www.frontiersin.org/articles/10.3389/fneur.2022.892480/full

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