HBV preS Mutations Promote Hepatocarcinogenesis by Inducing Endoplasmic Reticulum Stress and Upregulating Inflammatory Signaling

HBV preS Mutations Promote Hepatocarcinogenesis by Inducing Endoplasmic Reticulum Stress and Upregulating Inflammatory Signaling

This study aimed to elucidate the effects and underlying mechanisms of hepatitis B virus (HBV) preS mutations on hepatocarcinogenesis. The effect of the preS mutations on hepatocellular carcinoma (HCC) occurrence was evaluated using a prospective cohort study with 2114 HBV-infected patients, of whom...

Full description

Bibliographic Details
Main Authors: Wenbin Liu, Shiliang Cai, Rui Pu, Zixiong Li, Donghong Liu, Xinyu Zhou, Jianhua Yin, Xi Chen, Liping Chen, Jianfeng Wu, Xiaojie Tan, Xin Wang, Guangwen Cao
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cancers
Subjects:
hepatitis B virus
preS mutation
carcinogenesis
inflammation
STAT3
Online Access:https://www.mdpi.com/2072-6694/14/13/3274

Internet

https://www.mdpi.com/2072-6694/14/13/3274

Similar Items