Hippocampal gray matter volume alterations in patients with first-episode and recurrent major depressive disorder and their associations with gene profiles

Hippocampal gray matter volume alterations in patients with first-episode and recurrent major depressive disorder and their associations with gene profiles

Abstract Background Recent studies indicate that patients with first-episode drug-naïve (FEDN) and recurrent major depressive disorder (R-MDD) exhibit distinct atrophy patterns in the hippocampal subregions along the proximal-distal axis. However, it remains unclear whether such differences occur al...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Fenfen Sun, Yifan Shuai, Jingru Wang, Jin Yan, Bin Lin, Xinyun Li, Zhiyong Zhao
Format: Artikel
Sprache:English
Veröffentlicht: BMC 2025-02-01
Schriftenreihe:BMC Psychiatry
Schlagworte:
Major depressive disorder
Hippocampal subfields
Magnetic resonance imaging
Gray matter volume
Gene expression
Online Zugang:https://doi.org/10.1186/s12888-025-06562-4

Online

https://doi.org/10.1186/s12888-025-06562-4

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