Functional complexity of hair follicle stem cell niche and therapeutic targeting of niche dysfunction for hair regeneration

Functional complexity of hair follicle stem cell niche and therapeutic targeting of niche dysfunction for hair regeneration

Abstract Stem cell activity is subject to non-cell-autonomous regulation from the local microenvironment, or niche. In adaption to varying physiological conditions and the ever-changing external environment, the stem cell niche has evolved with multifunctionality that enables stem cells to detect th...

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Bibliographic Details
Main Authors: Chih-Lung Chen, Wen-Yen Huang, Eddy Hsi Chun Wang, Kang-Yu Tai, Sung-Jan Lin
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Journal of Biomedical Science
Subjects:
Hair follicle stem cell
Niche
Function
Alopecia
Alopecia areata
Lichen planopilaris
Online Access:http://link.springer.com/article/10.1186/s12929-020-0624-8

Internet

http://link.springer.com/article/10.1186/s12929-020-0624-8

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