Enhancing the Immunogenicity of Vaccinia Virus

Enhancing the Immunogenicity of Vaccinia Virus

The conventional live smallpox vaccine based on the vaccinia virus (VACV) cannot be widely used today because it is highly reactogenic. Therefore, there is a demand for designing VACV variants possessing enhanced immunogenicity, making it possible to reduce the vaccine dose and, therefore, significa...

Full description

Bibliographic Details
Main Authors: Sergei N. Shchelkunov, Stanislav N. Yakubitskiy, Alexander A. Sergeev, Ekaterina V. Starostina, Ksenia A. Titova, Stepan A. Pyankov, Galina A. Shchelkunova, Mariya B. Borgoyakova, Alexey M. Zadorozhny, Lyubov A. Orlova, Denis N. Kisakov, Larisa I. Karpenko
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Viruses
Subjects:
poxviruses
vaccinia virus
vaccines
adaptive immune response
antibodies
T cells
Online Access:https://www.mdpi.com/1999-4915/14/7/1453

Internet

https://www.mdpi.com/1999-4915/14/7/1453

Similar Items