Macroscopic Dynamic Modeling of Sequential Batch Cultures of Hybridoma Cells: An Experimental Validation
Hybridoma cells are commonly grown for the production of monoclonal antibodies (MAb). For monitoring and control purposes of the bioreactors, dynamic models of the cultures are required. However these models are difficult to infer from the usually limited amount of available experimental data and do...
Main Authors: | Laurent Dewasme, François Côte, Patrice Filee, Anne-Lise Hantson, Alain Vande Wouwer |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-02-01
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Series: | Bioengineering |
Subjects: | |
Online Access: | http://www.mdpi.com/2306-5354/4/1/17 |
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