1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) attenuates gemcitabine-induced neutrophil extravasation

1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) attenuates gemcitabine-induced neutrophil extravasation

Abstract Cancer patients treated with chemotherapy often experience a rapid decline of blood neutrophils, a dose-limiting side effect called chemotherapy-induced neutropenia. This complication brings about dose reductions or cessation of chemotherapy during treatment of cancer patients because a rap...

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Bibliographic Details
Main Authors: Jinseon Jeong, Yong-Jae Kim, Do Young Lee, Byoung-Gon Moon, Ki-Young Sohn, Sun Young Yoon, Jae Wha Kim
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Cell & Bioscience
Subjects:
PLAG
Gemcitabine
Chemotherapy induced neutropenia (CIN)
Chemokine
Reactive oxygen species
NADPH oxidase 2
Online Access:http://link.springer.com/article/10.1186/s13578-018-0266-7

Internet

http://link.springer.com/article/10.1186/s13578-018-0266-7

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