Vancomycin tolerance of adherent Staphylococcus aureus is impeded by nanospike-induced physiological changes

Abstract Bacterial colonization of implantable biomaterials is an ever-pervasive threat that causes devastating infections, yet continues to elude resolution. In the present study, we report how a rationally designed antibacterial surface containing sharp nanospikes can enhance the susceptibility of...

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Bibliographic Details
Main Authors: Andrew Hayles, Richard Bright, Ngoc Huu Nguyen, Vi Khanh Truong, Jonathan Wood, Dennis Palms, Jitraporn Vongsvivut, Dan Barker, Krasimir Vasilev
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-023-00458-5