Targeting the RNA-Binding Protein HuR as Potential Thera-Peutic Approach for Neurological Disorders: Focus on Amyo-Trophic Lateral Sclerosis (ALS), Spinal Muscle Atrophy (SMA) and Multiple Sclerosis

Targeting the RNA-Binding Protein HuR as Potential Thera-Peutic Approach for Neurological Disorders: Focus on Amyo-Trophic Lateral Sclerosis (ALS), Spinal Muscle Atrophy (SMA) and Multiple Sclerosis

The importance of precise co- and post-transcriptional processing of RNA in the regulation of gene expression has become increasingly clear. RNA-binding proteins (RBPs) are a class of proteins that bind single- or double-chain RNA, with different affinities and selectivity, thus regulating the vario...

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Bibliographic Details
Main Authors: Vittoria Borgonetti, Elisabetta Coppi, Nicoletta Galeotti
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
RNA-binding proteins (RPBs)
ELAV/Hu
HuR
neurodegenerative disease
neuroinflammation
neuroprotection
Online Access:https://www.mdpi.com/1422-0067/22/19/10394

Internet

https://www.mdpi.com/1422-0067/22/19/10394

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