A Core Transcription Regulatory Circuitry Defining Microglia Cell Identity Inferred from the Reanalysis of Multiple Human Microglia Differentiation Protocols

Microglia, the immune cells in the brain involved in both homeostasis and injury/infection control, play a predominant role in neurodegenerative diseases. In vivo studies on microglia are limited due to the requirement of surgical intervention, which can lead to the destruction of the tissues. Over...

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Bibliographic Details
Main Authors: Antoine Aubert, François Stüder, Bruno Maria Colombo, Marco Antonio Mendoza-Parra
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/11/10/1338