S100a9 inhibits Atg9a transcription and participates in suppression of autophagy in cardiomyocytes induced by β1-adrenoceptor autoantibodies

S100a9 inhibits Atg9a transcription and participates in suppression of autophagy in cardiomyocytes induced by β1-adrenoceptor autoantibodies

Abstract Background Cardiomyocyte death induced by autophagy inhibition is an important cause of cardiac dysfunction. In-depth exploration of its mechanism may help to improve cardiac dysfunction. In our previous study, we found that β1-adrenergic receptor autoantibodies (β1-AAs) induced a decrease...

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Bibliographic Details
Main Authors: Xiaoyan Zhi, Shu Shi, Yang Li, Mingxia Ma, Yaolin Long, Chen Li, Haihu Hao, Huirong Liu, Xiaohui Wang, Li Wang
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Cellular & Molecular Biology Letters
Subjects:
S100a9
β1-AA
Autophagy
HIF-1α
Atg9a
Online Access:https://doi.org/10.1186/s11658-023-00486-1

Internet

https://doi.org/10.1186/s11658-023-00486-1

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