Diagnostic utility of immunohistochemistry in detection of NPM1 mutations in acute myeloid leukemia with a patchy distribution
Abstract Nucleophosmin 1 (NPM1) mutations occur in approximately one‐third cases of adult de novo acute myeloid leukemia (AML). Identification of NPM1 mutations is important for classification, risk stratification, tailored therapy, and monitoring minimal residual disease. Mutational analysis is wid...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2024-04-01
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Series: | eJHaem |
Subjects: | |
Online Access: | https://doi.org/10.1002/jha2.866 |