Diagnostic utility of immunohistochemistry in detection of NPM1 mutations in acute myeloid leukemia with a patchy distribution

Diagnostic utility of immunohistochemistry in detection of NPM1 mutations in acute myeloid leukemia with a patchy distribution

Abstract Nucleophosmin 1 (NPM1) mutations occur in approximately one‐third cases of adult de novo acute myeloid leukemia (AML). Identification of NPM1 mutations is important for classification, risk stratification, tailored therapy, and monitoring minimal residual disease. Mutational analysis is wid...

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Bibliographic Details
Main Authors: Qing Wei, Sa A. Wang, Sanam Loghavi, Hong Fang, L. Jeffrey Medeiros, Wei Wang
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:eJHaem
Subjects:
acute myeloid leukemia
immunohistochemistry
NPM1
Online Access:https://doi.org/10.1002/jha2.866

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