Integrating Multi-Omics with environmental data for precision health: A novel analytic framework and case study on prenatal mercury induced childhood fatty liver disease

Integrating Multi-Omics with environmental data for precision health: A novel analytic framework and case study on prenatal mercury induced childhood fatty liver disease

Background: Precision Health aims to revolutionize disease prevention by leveraging information across multiple omic datasets (multi-omics). However, existing methods generally do not consider personalized environmental risk factors (e.g., environmental pollutants). Objective: To develop and apply a...

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Autors principals: Jesse A. Goodrich, Hongxu Wang, Qiran Jia, Nikos Stratakis, Yinqi Zhao, Léa Maitre, Mariona Bustamante, Marina Vafeiadi, Max Aung, Sandra Andrušaitytė, Xavier Basagana, Shohreh F. Farzan, Barbara Heude, Hector Keun, Rob McConnell, Tiffany C. Yang, Alexandros P. Siskos, Jose Urquiza, Damaskini Valvi, Nerea Varo, Line Småstuen Haug, Bente M. Oftedal, Regina Gražulevičienė, Claire Philippat, John Wright, Martine Vrijheid, Leda Chatzi, David V. Conti
Format: Article
Idioma:English
Publicat: Elsevier 2024-08-01
Col·lecció:Environment International
Matèries:
Precision health
Multiomics
Epigenetics
Prenatal exposures
Bioinformatics
Biomarkers
Accés en línia:http://www.sciencedirect.com/science/article/pii/S0160412024005166

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http://www.sciencedirect.com/science/article/pii/S0160412024005166

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