Promoter/enhancer-based controllability of regulatory networks

Abstract Understanding the mechanisms of tissue-specific transcriptional regulation is crucial as mis-regulation can cause a broad range of diseases. Here, we investigated transcription factors (TF) that are indispensable for the topological control of tissue specific and cell-type specific regulato...

Full description

Bibliographic Details
Main Authors: Prajwal Devkota, Stefan Wuchty
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-07035-4